

Spider-Man defeats Carnage, who gets sucked back into space with the other symbiotes. Suddenly, the symbiotes come through a portal in the sky. Doctor Octopus suddenly attacks them, but his new arms are prototypes and begin to explode, causing Spider-Man to celebrate in triumph. The Venom symbiote leaves Eddie Brock, who informs Spider-Man of Carnage's plan to destroy New York. Venom ambushes the Goblin Glider, but Spider-Man stops him. Later, Octopus sends Green Goblin after Spider-Man, and he chases him across the city. Meanwhile, Spider-Man tracks the GPS to Octopus' old arms, where he ambushed by Smythe. After realizing someone is tracking him using the GPS, Octopus gains Mark II arms with more tentacles and forcefully transforms Alistair Smythe into a human/Spider Slayer hybrid.

Mysterio, hearing of Octopus' plans, traps Spider-Man in his headquarters, but Spider-Man defeats him and realizes he left a GPS that tracks Octopus' arms (given to Mysterio when he last helped Octopus). Spider-Man defeats Beetle, and also defeats Lizard and uses the antidote on him, though it only takes him out of Octopus' control. Meanwhile, astronaut John Jameson is attacked by a red and black goo on his spaceship. While Spider-Man manages to defeat the Spider Slayers, Beetle escapes and is subsequently hired by Octopus. Meanwhile, Spider-Man attempts to stop Beetle from robbing a bank, but is attacked by the Spider Slayers. Thus, Lizard becomes Octopus' new employee, while Octopus hires scientist Spencer Smythe to create the Spider Slayers and attack Spider-Man. Connors attempts to use the Lizard serum to increase his power, but fails. In addition friendly characters including Human Torch, Speedball, and Iron Fist appear in cutscenes in between levels.Īdditional content was unlocked by scanning barcodes with Barcode Battler II connected via a "Barcode Battler II Interface".Īfter past defeats, Doctor Octopus escapes from prison and forces Curt Connors to help him. Spider-Man battles various villains throughout the game – Spider-Slayers, Beetle, Lizard, Mysterio, Alistair Smythe, Green Goblin, Scorpion, Venom, Doctor Octopus, and Carnage. Each level has a timed checkpoint within each level, as players must reach their destination within the time limit. Spider-Man's web-swinging abilities can be used to get to various places. One of the villains in the game is the Beetle.
